Changes in growth factors in polycystic ovarian syndrome
نویسندگان
چکیده
Background. Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting 10-15% of women reproductive age. PCOS often associated with metabolic disorders, type 2 diabetes, cardiovascular disease, and other complications. In recent years, angiogenesis has been widely discussed as an important factor in pathogenesis PCOS. Objective. To identify growth factors compared healthy normal overweight subgroups. Design methods. This case-control study carried out at Almazov National Medical Research Centre (ANMRC) included 45 patients (22 a body mass index (BMI) < 25 kg/m 23 BMI > ) ovulation ). Seven were analyzed plasma patients. Results. Compared to control group, weight had higher levels EGF (medians 5.57 0 pg/ml, p = 0.040) FLT3L 5.0 2.25 0.018). Growth FGF TGF alpha increased both subgroups (p<0.001). Conclusion. non-overweight groups, show increase factors.
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ژورنال
عنوان ژورنال: ?????????????? ????????
سال: 2023
ISSN: ['2782-389X', '2409-5516']
DOI: https://doi.org/10.18705/2311-44952023-10-2-77-87